Welcome!

Our research has two, closely related goals. One goal is to better understand how genes and neural networks in the brain and spinal cord control movement. More recently, we’ve establish a second goal, which is provide new insight into epilepsy and develop new therapeutics to treat these disorders.

To pursue both of our research goals we use zebrafish. Developing zebrafish have several features that make it a great model system. The embryos and larvae develop quickly, exhibit strong motor behavior, are transparent so their brains can be easily observed, and we can use the power of zebrafish genetics to investigate how genes regulate nervous system function. These features allow us to take an integrated genetic, microscopic imaging, and behavioral approach to study the neural networks that control movement. Since many genes and aspects of brain function are conserved among vertebrates, developing zebrafish offer many advantages to model genetic epilepsies, investigate how neural networks are disrupted to cause seizures, and establish a high-throughput platform to identify new therapeutic compounds.

The Latest:

September 2019-  A new academic year, and new students. We welcome Madison Riffe, a new Neuroscience and Behavior PhD student, and Ben Clayton, an undergraduate, to the lab. We’re glad you’re here and can’t wait to see what you discover!

May 2019 – Graduation season and it’s time to celebrate, although we’re sad to see undergraduates Sarah and Ana leave the lab. It’s been great to have such excellent students, and they both did an outstanding job completing their capstone projects. It’s also thrilling to hear the news about former students beginning the next phase of their careers. Abby Case is enrolling in Medical School at Quinnipiac University, Bahati N’kera is enrolling in the Neuroscience PhD program at Brown University, and Chris Huenneke is enrolling in Medical School at Harvard University. Bravo! We’re so proud of all of you!!

February  2019 – Wayne passed Comps I, a big hurdle in his PhD program! Way to go!